| Authors: | Gregory Z. Ferl |
| Title: | [download] (1381)DATforDCEMRI: An R Package for Deconvolution Analysis and Visualization of DCE-MRI Data |
| Reference: | Vol. 44, Issue 3, Oct 2011 Submitted 2010-10-11, Accepted 2011-06-22 |
| Type: | Article |
| Abstract: | Numerical deconvolution is a powerful mathematical operation that can be used to extract the impulse response function of a linear, time-invariant system. We have found this method to be useful for preliminary analysis of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) data, capable of quickly producing voxel-wise parametric maps describing the heterogeneity of contrast agent kinetics over the entire field of view, typically comprising tens of thousands of voxels. The statistical programming language R is well suited for this type of analysis and when combined with LATEX, via Sweave, allows one to perform all calculations and generate a report with a single script. The purpose of this manuscript is to describe the R package DATforDCEMRI, a Deconvolution Analysis Tool for DCE-MRI contrast agent concentration vs. time data, which allows the user to perform kinetic deconvolution analysis and visualize/explore the resulting voxel-wise parametric maps and associated data. |
| Paper: | [download] (1381)DATforDCEMRI: An R Package for Deconvolution Analysis and Visualization of DCE-MRI Data (application/pdf, 2.7 MB) |
| Supplements: | [download] (667)DATforDCEMRI_0.51.tar.gz: R source package (application/x-gzip, 3 MB) |
| [download] (309)v44i03.R: R example code from the paper (application/octet-stream, 456 Bytes) |
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| [download] (327)Downloading-data.txt: Example Data downloading instructions (text/plain, 154 Bytes) |
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| Resources: | BibTeX | OAI |
