Published by the Foundation for Open Access Statistics
Editors-in-chief: Bettina GrĂ¼n, Edzer Pebesma & Achim Zeileis    ISSN 1548-7660; CODEN JSSOBK
EMMIXuskew: An R Package for Fitting Mixtures of Multivariate Skew t Distributions via the EM Algorithm | McLachlan | Journal of Statistical Software
Authors: Geoff McLachlan, Sharon X Lee
Title: EMMIXuskew: An R Package for Fitting Mixtures of Multivariate Skew t Distributions via the EM Algorithm
Abstract: This paper describes an algorithm for fitting finite mixtures of unrestricted Multivariate Skew t (FM-uMST) distributions. The package EMMIXuskew implements a closed-form expectation-maximization (EM) algorithm for computing the maximum likelihood (ML) estimates of the parameters for the (unrestricted) FM-MST model in R. EMMIXuskew also supports visualization of fitted contours in two and three dimensions, and random sample generation from a specified FM-uMST distribution.
Finite mixtures of skew t distributions have proven to be useful in modelling heterogeneous data with asymmetric and heavy tail behaviour, for example, datasets from flow cytometry. In recent years, various versions of mixtures with multivariate skew t (MST) distributions have been proposed. However, these models adopted some restricted characterizations of the component MST distributions so that the E-step of the EM algorithm can be evaluated in closed form. This paper focuses on mixtures with unrestricted MST components, and describes an iterative algorithm for the computation of the ML estimates of its model parameters. Its implementation in R is presented with the package EMMIXuskew.
The usefulness of the proposed algorithm is demonstrated in three applications to real datasets. The first example illustrates the use of the main function fmmst in the package by fitting a MST distribution to a bivariate unimodal flow cytometric sample. The second example fits a mixture of MST distributions to the Australian Institute of Sport (AIS) data, and demonstrates that EMMIXuskew can provide better clustering results than mixtures with restricted MST components. In the third example, EMMIXuskew is applied to classify cells in a trivariate flow cytometric dataset. Comparisons with some other available methods suggest that EMMIXuskew achieves a lower misclassification rate with respect to the labels given by benchmark gating analysis.

Page views:: 3108. Submitted: 2012-02-03. Published: 2013-11-20.
Paper: EMMIXuskew: An R Package for Fitting Mixtures of Multivariate Skew t Distributions via the EM Algorithm     Download PDF (Downloads: 3261)
Supplements:
EMMIXuskew_0.11-5.tar.gz: R source package Download (Downloads: 250; 200KB)
v55i12.R: R example code from the paper Download (Downloads: 266; 5KB)
DLBCL.zip: DLBCL data and parameter settings Download (Downloads: 263; 43KB)

DOI: 10.18637/jss.v055.i12

by
This work is licensed under the licenses
Paper: Creative Commons Attribution 3.0 Unported License
Code: GNU General Public License (at least one of version 2 or version 3) or a GPL-compatible license.