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Editors-in-chief: Bettina Grün, Torsten Hothorn, Edzer Pebesma, Achim Zeileis    ISSN 1548-7660; CODEN JSSOBK
A SAS Macro for Covariate-Constrained Randomization of General Cluster-Randomized and Unstratified Designs | Greene | Journal of Statistical Software
Authors: Erich J. Greene
Title: A SAS Macro for Covariate-Constrained Randomization of General Cluster-Randomized and Unstratified Designs
Abstract: Ivers et al. (2012) have recently stressed the importance to both statistical power and face validity of balancing allocations to study arms on relevant covariates. While several techniques exist (e.g., minimization, pair-matching, stratification), the covariateconstrained randomization (CCR) approach proposed by Moulton (2004) is favored when clusters can be recruited prior to randomization. CCRA V1.0, a macro published by Chaudhary and Moulton (2006), provides a SAS implementation of CCR for a particular subset of possible designs (those with two arms, small numbers of strata and clusters, an equal number of clusters within each stratum, and constraints that can be expressed as absolute mean differences between arms). This paper presents a more comprehensive macro, CCR, that is applicable across a wider variety of designs and provides statistics describing the range of possible allocations meeting the constraints in addition to performing the actual random assignment.

Page views:: 904. Submitted: 2015-06-23. Published: 2017-04-03.
Paper: A SAS Macro for Covariate-Constrained Randomization of General Cluster-Randomized and Unstratified Designs     Download PDF (Downloads: 252)
Supplements:
CCR.zip: SAS source code Download (Downloads: 24; 30KB)
v77c01.sas: SAS replication code Download (Downloads: 20; 67KB)
v77c01-replication.pdf: Replication output Download (Downloads: 21; 202KB)

DOI: 10.18637/jss.v077.c01

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Paper: Creative Commons Attribution 3.0 Unported License
Code: GNU General Public License (at least one of version 2 or version 3) or a GPL-compatible license.