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Despite the large body of research on missing value distributions and imputation, there is comparatively little literature with a focus on how to make it easy to handle, explore, and impute missing values in data. This paper addresses this gap. The new methodology builds upon tidy data principles, with the goal of integrating missing value handling as a key part of data analysis workflows. We define a new data structure, and a suite of new operations. Together, these provide a connected framework for handling, exploring, and imputing missing values. These methods are available in the R package naniar.